Wednesday February 22, 2012

5 things about the science of IGF-1

We might not be too familiar with the term IGF-1 but it is a very important phenomenon. IGF stands for Insulin-like Growth Factor as its structure is similar to hormone insulin. The igf-1 and GH (Growth Hormone) have lots of similarities when it comes to action. This is also due to the binding of the growth hormone to GH receptors which results into a signal cascade which leads to the generation of igf-1. Like the Growth hormone, igf-1 efficiently enhances the protein anabolism.

  • IGF-1 has also been shown in both vivo and vitro and it clearly doesn’t possess the effects of lipolytic that the growth hormone exhibits for the sole reason that there is no type 1 IGF-1 receptor found in the adipocytes. This might be unanticipated for various weightlifters who utter profanities of the properties of fat loss of the IGF-1. IGF-1 acts just like insulin which does not come as a surprise and also the administration of the IGF-1 is towards low blood sugar or hypoglycaemic.
  • IGF-1 is very important when it comes to the action of insulin on the skeletal muscle. The igf-1 helps in improving insulin sensitivity which is really helpful for bodybuilders. But a little piece of advice is that if you start using IGF-1 and has not taken insulin previously then do not use it. If you are well-experienced in terms of insulin and then you start taking IGF-1 then the insulin dosage might wish to get lowered.
  • IGF-1 is not something inexpert bodybuilders should use. Before you start using IGF-1, you need to use anabolic steroid for a long duration. Also, you need to be well-aware of the effects of IGF-1 before you start using it since there are various side-effects and risks involved.
  • Risks include tumours, cancer or the enlarging of the intestinal organs. IGF-1 is something you cannot take lightly. You need to be a very experienced bodybuilder in order to take the igf-1.
  • The normal IGF-1 has a very short life and hence it is not recommended for people as it is highly unstable and sensitive. The properties of the normal IGF-1 are very unstable and hence are very rarely used. But there is a correspondent of IGF-1 known as Long R3IGF-1 which is preferred by many people.
The properties of this analogue is safer than IGF-1. The added advantage is that the administration of the R2IGF-1 is not as frequent like the normal IGF-1. So, in order to stay healthy – be at the safer side and do not use IGF-1 in case you are not experienced.
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